Mutation mapping and identification by whole-genome sequencing

Genetic mapping of mutations in model systems has facilitated the identification of genes contributing to fundamental biological processes including human diseases. However, this approach has historically required the prior characterization of informative markers. Here we report a fast and cost-effe...

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Detalles Bibliográficos
Autores principales: Leshchiner, Ignaty, Alexa, Kristen, Kelsey, Peter, Adzhubei, Ivan, Austin-Tse, Christina A., Cooney, Jeffrey D., Anderson, Heidi, King, Matthew J., Stottmann, Rolf W., Garnaas, Maija K., Ha, Seungshin, Drummond, Iain A., Paw, Barry H., North, Trista E., Beier, David R., Goessling, Wolfram, Sunyaev, Shamil R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2012
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3409267/
https://www.ncbi.nlm.nih.gov/pubmed/22555591
http://dx.doi.org/10.1101/gr.135541.111

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