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CCL2 Disrupts the Adherens Junction: Implications for Neuroinflammation
Alterations to blood-brain barrier (BBB) adhesion molecules and junctional integrity during neuroinflammation can promote central nervous system (CNS) pathology. The chemokine CCL2 is elevated during CNS inflammation and is associated with endothelial dysfunction. The effects of CCL2 on endothelial...
Autores principales: | Roberts, Toni K., Eugenin, Eliseo A., Lopez, Lillie, Romero, Ignacio A., Weksler, Babette B., Couraud, Pierre-Olivier, Berman, Joan W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3409314/ https://www.ncbi.nlm.nih.gov/pubmed/22641100 http://dx.doi.org/10.1038/labinvest.2012.80 |
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