Immune Activation and CD8(+) T-Cell Differentiation towards Senescence in HIV-1 Infection

Progress in the fight against the HIV/AIDS epidemic is hindered by our failure to elucidate the precise reasons for the onset of immunodeficiency in HIV-1 infection. Increasing evidence suggests that elevated immune activation is associated with poor outcome in HIV-1 pathogenesis. However, the basis...

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Detalles Bibliográficos
Autores principales: Papagno, Laura, Spina, Celsa A, Marchant, Arnaud, Salio, Mariolina, Rufer, Nathalie, Little, Susan, Dong, Tao, Chesney, Gillian, Waters, Anele, Easterbrook, Philippa, Dunbar, P. Rod, Shepherd, Dawn, Cerundolo, Vincenzo, Emery, Vincent, Griffiths, Paul, Conlon, Christopher, McMichael, Andrew J, Richman, Douglas D, Rowland-Jones, Sarah L, Appay, Victor
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2004
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC340937/
https://www.ncbi.nlm.nih.gov/pubmed/14966528
http://dx.doi.org/10.1371/journal.pbio.0020020

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