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Dominance of the CD4(+) T helper cell response during acute resolving hepatitis A virus infection
Hepatitis A virus (HAV) infection typically resolves within 4–7 wk but symptomatic relapse occurs in up to 20% of cases. Immune mechanisms that terminate acute HAV infection, and prevent a relapse of virus replication and liver disease, are unknown. Here, patterns of T cell immunity, virus replicati...
Autores principales: | Zhou, Yan, Callendret, Benoît, Xu, Dan, Brasky, Kathleen M., Feng, Zongdi, Hensley, Lucinda L., Guedj, Jeremie, Perelson, Alan S., Lemon, Stanley M., Lanford, Robert E., Walker, Christopher M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3409494/ https://www.ncbi.nlm.nih.gov/pubmed/22753925 http://dx.doi.org/10.1084/jem.20111906 |
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