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Primary Burkitt's Lymphoma Presenting as a Rapidly Growing Thyroid Mass

A 31-year-old male patient presented with a rapidly growing neck mass with normal thyroid function tests. Ultrasonography showed thyroidal expansion, a hypoechoic nodule that completely filled the right lobe, and 2 hypoechoic lymphadenopathies in the right jugulodigastric chain. The patient underwen...

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Autores principales: Yildiz, Ibrahim, Sen, Fatma, Toz, Bahtiyar, Kilic, Leyla, Agan, Mehmet, Basaran, Mert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3409505/
https://www.ncbi.nlm.nih.gov/pubmed/23524885
http://dx.doi.org/10.1159/000341260
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author Yildiz, Ibrahim
Sen, Fatma
Toz, Bahtiyar
Kilic, Leyla
Agan, Mehmet
Basaran, Mert
author_facet Yildiz, Ibrahim
Sen, Fatma
Toz, Bahtiyar
Kilic, Leyla
Agan, Mehmet
Basaran, Mert
author_sort Yildiz, Ibrahim
collection PubMed
description A 31-year-old male patient presented with a rapidly growing neck mass with normal thyroid function tests. Ultrasonography showed thyroidal expansion, a hypoechoic nodule that completely filled the right lobe, and 2 hypoechoic lymphadenopathies in the right jugulodigastric chain. The patient underwent right total and left subtotal thyroidectomy, following the diagnosis of nodular goiter; however, postoperative histopathological evaluation demonstrated primary Burkitt's lymphoma of the thyroid gland. The tumor was staged as stage 1, and R-hyper-CVAD protocol (rituximab, hyperfractionated cyclophosphamide, vincristine, doxorubicin and dexamethasone) was administered. The protocol was changed to R-CHOP after 4 cycles due to recurrent grade III/IV cytopenias and febrile neutropenia. The PET-CT scans performed after chemotherapy and at the 6-month follow-up were normal. In summary, we reported a case with a diagnosis of Burkitt's lymphoma, which is a rare type of primary thyroid lymphoma.
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spelling pubmed-34095052013-03-22 Primary Burkitt's Lymphoma Presenting as a Rapidly Growing Thyroid Mass Yildiz, Ibrahim Sen, Fatma Toz, Bahtiyar Kilic, Leyla Agan, Mehmet Basaran, Mert Case Rep Oncol Published online: July, 2012 A 31-year-old male patient presented with a rapidly growing neck mass with normal thyroid function tests. Ultrasonography showed thyroidal expansion, a hypoechoic nodule that completely filled the right lobe, and 2 hypoechoic lymphadenopathies in the right jugulodigastric chain. The patient underwent right total and left subtotal thyroidectomy, following the diagnosis of nodular goiter; however, postoperative histopathological evaluation demonstrated primary Burkitt's lymphoma of the thyroid gland. The tumor was staged as stage 1, and R-hyper-CVAD protocol (rituximab, hyperfractionated cyclophosphamide, vincristine, doxorubicin and dexamethasone) was administered. The protocol was changed to R-CHOP after 4 cycles due to recurrent grade III/IV cytopenias and febrile neutropenia. The PET-CT scans performed after chemotherapy and at the 6-month follow-up were normal. In summary, we reported a case with a diagnosis of Burkitt's lymphoma, which is a rare type of primary thyroid lymphoma. S. Karger AG 2012-07-24 /pmc/articles/PMC3409505/ /pubmed/23524885 http://dx.doi.org/10.1159/000341260 Text en Copyright © 2012 by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-Noncommercial-No-Derivative-Works License (http://creativecommons.org/licenses/by-nc-nd/3.0/). Users may download, print and share this work on the Internet for noncommercial purposes only, provided the original work is properly cited, and a link to the original work on http://www.karger.com and the terms of this license are included in any shared versions.
spellingShingle Published online: July, 2012
Yildiz, Ibrahim
Sen, Fatma
Toz, Bahtiyar
Kilic, Leyla
Agan, Mehmet
Basaran, Mert
Primary Burkitt's Lymphoma Presenting as a Rapidly Growing Thyroid Mass
title Primary Burkitt's Lymphoma Presenting as a Rapidly Growing Thyroid Mass
title_full Primary Burkitt's Lymphoma Presenting as a Rapidly Growing Thyroid Mass
title_fullStr Primary Burkitt's Lymphoma Presenting as a Rapidly Growing Thyroid Mass
title_full_unstemmed Primary Burkitt's Lymphoma Presenting as a Rapidly Growing Thyroid Mass
title_short Primary Burkitt's Lymphoma Presenting as a Rapidly Growing Thyroid Mass
title_sort primary burkitt's lymphoma presenting as a rapidly growing thyroid mass
topic Published online: July, 2012
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3409505/
https://www.ncbi.nlm.nih.gov/pubmed/23524885
http://dx.doi.org/10.1159/000341260
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