Keratin Expression in Mammary Paget's Disease in situ with Intraductal Invasion

We performed immunohistochemical studies of epithelial keratins in intraductal carcinoma in situ (IDCIS) in mammary Paget's disease (MPD). K7, K8 and K18 were expressed in IDCIS in MPD. However, K19 was not expressed in IDCIS in MPD. Interestingly, K17 was expressed in some tumor cells in IDCIS...

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Autores principales: Kurokawa, Ichiro, Furukawa, Sayaka, Kishimoto, Masahiro, Kakuno, Ayako, Tsubura, Airo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2012
Materias:
Published online: July, 2012
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3409513/
https://www.ncbi.nlm.nih.gov/pubmed/23525171
http://dx.doi.org/10.1159/000341663
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author Kurokawa, Ichiro
Furukawa, Sayaka
Kishimoto, Masahiro
Kakuno, Ayako
Tsubura, Airo
author_facet Kurokawa, Ichiro
Furukawa, Sayaka
Kishimoto, Masahiro
Kakuno, Ayako
Tsubura, Airo
author_sort Kurokawa, Ichiro
collection PubMed
description We performed immunohistochemical studies of epithelial keratins in intraductal carcinoma in situ (IDCIS) in mammary Paget's disease (MPD). K7, K8 and K18 were expressed in IDCIS in MPD. However, K19 was not expressed in IDCIS in MPD. Interestingly, K17 was expressed in some tumor cells in IDCIS. K17, a hyperproliferative keratin, may suggest ductal invasion and poor prognosis in MPD.
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spelling pubmed-34095132013-03-22 Keratin Expression in Mammary Paget's Disease in situ with Intraductal Invasion Kurokawa, Ichiro Furukawa, Sayaka Kishimoto, Masahiro Kakuno, Ayako Tsubura, Airo Case Rep Oncol Published online: July, 2012 We performed immunohistochemical studies of epithelial keratins in intraductal carcinoma in situ (IDCIS) in mammary Paget's disease (MPD). K7, K8 and K18 were expressed in IDCIS in MPD. However, K19 was not expressed in IDCIS in MPD. Interestingly, K17 was expressed in some tumor cells in IDCIS. K17, a hyperproliferative keratin, may suggest ductal invasion and poor prognosis in MPD. S. Karger AG 2012-07-24 /pmc/articles/PMC3409513/ /pubmed/23525171 http://dx.doi.org/10.1159/000341663 Text en Copyright © 2012 by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-Noncommercial-No-Derivative-Works License (http://creativecommons.org/licenses/by-nc-nd/3.0/). Users may download, print and share this work on the Internet for noncommercial purposes only, provided the original work is properly cited, and a link to the original work on http://www.karger.com and the terms of this license are included in any shared versions.
spellingShingle Published online: July, 2012
Kurokawa, Ichiro
Furukawa, Sayaka
Kishimoto, Masahiro
Kakuno, Ayako
Tsubura, Airo
Keratin Expression in Mammary Paget's Disease in situ with Intraductal Invasion
title Keratin Expression in Mammary Paget's Disease in situ with Intraductal Invasion
title_full Keratin Expression in Mammary Paget's Disease in situ with Intraductal Invasion
title_fullStr Keratin Expression in Mammary Paget's Disease in situ with Intraductal Invasion
title_full_unstemmed Keratin Expression in Mammary Paget's Disease in situ with Intraductal Invasion
title_short Keratin Expression in Mammary Paget's Disease in situ with Intraductal Invasion
title_sort keratin expression in mammary paget's disease in situ with intraductal invasion
topic Published online: July, 2012
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3409513/
https://www.ncbi.nlm.nih.gov/pubmed/23525171
http://dx.doi.org/10.1159/000341663
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