Cargando…
Membrane protein sequestering by ionic protein-lipid interactions
Neuronal exocytosis is catalyzed by the SNARE protein syntaxin-1A(1). Syntaxin-1A is clustered in the plasma membrane at sites where synaptic vesicles undergo exocytosis(2,3). However, how syntaxin-1A is sequestered is unknown. Here, we show that syntaxin clustering is mediated by electrostatic inte...
Autores principales: | van den Bogaart, Geert, Meyenberg, Karsten, Risselada, H. Jelger, Amin, Hayder, Willig, Katrin I., Hubrich, Barbara E., Dier, Markus, Hell, Stefan W., Grubmüller, Helmut, Diederichsen, Ulf, Jahn, Reinhard |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3409895/ https://www.ncbi.nlm.nih.gov/pubmed/22020284 http://dx.doi.org/10.1038/nature10545 |
Ejemplares similares
-
Synaptotagmin-1 may be a distance regulator acting upstream of SNARE nucleation
por: van den Bogaart, Geert, et al.
Publicado: (2011) -
Phosphatidylinositol 4,5-bisphosphate clusters act as molecular beacons for vesicle recruitment
por: Honigmann, Alf, et al.
Publicado: (2013) -
Hydrophobic mismatch sorts SNARE proteins into distinct membrane domains
por: Milovanovic, Dragomir, et al.
Publicado: (2015) -
How proteins open fusion pores: insights from molecular simulations
por: Risselada, H. Jelger, et al.
Publicado: (2020) -
TatBC-Independent TatA/Tat Substrate Interactions Contribute to Transport Efficiency
por: Taubert, Johannes, et al.
Publicado: (2015)