Midazolam-induced acute dystonia reversed by diazepam

Midazolam can induce acute dystonia in childhood. We report the development of acute dystonia in a 6-year-old girl after receiving midazolam as a sedative. Dystonic contractions persisted despite flumazenil and biperiden lactate injections and the patient was treated with diazepam. Acute dystonia wa...

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Autores principales: Komur, Mustafa, Arslankoylu, Ali Ertug, Okuyaz, Cetin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2012
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3409951/
https://www.ncbi.nlm.nih.gov/pubmed/22869948
http://dx.doi.org/10.4103/0970-9185.98346
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author Komur, Mustafa
Arslankoylu, Ali Ertug
Okuyaz, Cetin
author_facet Komur, Mustafa
Arslankoylu, Ali Ertug
Okuyaz, Cetin
author_sort Komur, Mustafa
collection PubMed
description Midazolam can induce acute dystonia in childhood. We report the development of acute dystonia in a 6-year-old girl after receiving midazolam as a sedative. Dystonic contractions persisted despite flumazenil and biperiden lactate injections and the patient was treated with diazepam. Acute dystonia was rapidly abolished after the administration of diazepam intravenously. Diazepam may be an effective treatment option in patients who are unresponsive to flumazenil.
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spelling pubmed-34099512012-08-06 Midazolam-induced acute dystonia reversed by diazepam Komur, Mustafa Arslankoylu, Ali Ertug Okuyaz, Cetin J Anaesthesiol Clin Pharmacol Case Report Midazolam can induce acute dystonia in childhood. We report the development of acute dystonia in a 6-year-old girl after receiving midazolam as a sedative. Dystonic contractions persisted despite flumazenil and biperiden lactate injections and the patient was treated with diazepam. Acute dystonia was rapidly abolished after the administration of diazepam intravenously. Diazepam may be an effective treatment option in patients who are unresponsive to flumazenil. Medknow Publications & Media Pvt Ltd 2012 /pmc/articles/PMC3409951/ /pubmed/22869948 http://dx.doi.org/10.4103/0970-9185.98346 Text en Copyright: © Journal of Anaesthesiology Clinical Pharmacology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Komur, Mustafa
Arslankoylu, Ali Ertug
Okuyaz, Cetin
Midazolam-induced acute dystonia reversed by diazepam
title Midazolam-induced acute dystonia reversed by diazepam
title_full Midazolam-induced acute dystonia reversed by diazepam
title_fullStr Midazolam-induced acute dystonia reversed by diazepam
title_full_unstemmed Midazolam-induced acute dystonia reversed by diazepam
title_short Midazolam-induced acute dystonia reversed by diazepam
title_sort midazolam-induced acute dystonia reversed by diazepam
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3409951/
https://www.ncbi.nlm.nih.gov/pubmed/22869948
http://dx.doi.org/10.4103/0970-9185.98346
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