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The study of systemic general circulation disturbance during the initiation of therapeutic hypothermia: Pit fall of hypothermia

AIMS: Neurointensive care has reduced the mortality and improved the outcome of patients for severe brain damage, over recent decades, and made it possible to perform this therapy in safety. However, we have to understand the complications of this therapy well. The purpose of our study was to determ...

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Autores principales: Honda, Mitsuru, Yokota, Kyosuke, Ichibayashi, Ryo, Yoshihara, Katsunori, Masuda, Hiroyuki, Uekusa, Hiroyuki, Seiki, Yoshikatsu, Nomoto, Jun, Nagao, Takeki, Kishi, Taichi, Sase, Shigeru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3410162/
https://www.ncbi.nlm.nih.gov/pubmed/22870153
http://dx.doi.org/10.4103/1793-5482.98645
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author Honda, Mitsuru
Yokota, Kyosuke
Ichibayashi, Ryo
Yoshihara, Katsunori
Masuda, Hiroyuki
Uekusa, Hiroyuki
Seiki, Yoshikatsu
Nomoto, Jun
Nagao, Takeki
Kishi, Taichi
Sase, Shigeru
author_facet Honda, Mitsuru
Yokota, Kyosuke
Ichibayashi, Ryo
Yoshihara, Katsunori
Masuda, Hiroyuki
Uekusa, Hiroyuki
Seiki, Yoshikatsu
Nomoto, Jun
Nagao, Takeki
Kishi, Taichi
Sase, Shigeru
author_sort Honda, Mitsuru
collection PubMed
description AIMS: Neurointensive care has reduced the mortality and improved the outcome of patients for severe brain damage, over recent decades, and made it possible to perform this therapy in safety. However, we have to understand the complications of this therapy well. The purpose of our study was to determine the systemic circulation disturbance during the initiation of therapeutic hypothermia by using this continuous neurointensive monitoring system. MATERIALS AND METHODS: Ten severe brain damage patients treated with hypothermia were enrolled. All patients had Glasgow Coma Scale (GCS) less than or equal to 8, on admission. RESULTS: We verified that heart rate, cardiac output, and oxygen delivery index (DO2I) decreased with decreasing core temperature. We recognized that depressed cardiac index (CI) was attributed to bradycardia, dehydration, and increased systemic vascular resistance index (SVRI) upon initiation of hypothermia. CONCLUSION: Although the hypothermia has a therapeutic role in severe brain damage patients, we have to carry out this therapy while maintaining their cardiac output using multimodality monitoring devices during hypothermia period.
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spelling pubmed-34101622012-08-06 The study of systemic general circulation disturbance during the initiation of therapeutic hypothermia: Pit fall of hypothermia Honda, Mitsuru Yokota, Kyosuke Ichibayashi, Ryo Yoshihara, Katsunori Masuda, Hiroyuki Uekusa, Hiroyuki Seiki, Yoshikatsu Nomoto, Jun Nagao, Takeki Kishi, Taichi Sase, Shigeru Asian J Neurosurg Original Article AIMS: Neurointensive care has reduced the mortality and improved the outcome of patients for severe brain damage, over recent decades, and made it possible to perform this therapy in safety. However, we have to understand the complications of this therapy well. The purpose of our study was to determine the systemic circulation disturbance during the initiation of therapeutic hypothermia by using this continuous neurointensive monitoring system. MATERIALS AND METHODS: Ten severe brain damage patients treated with hypothermia were enrolled. All patients had Glasgow Coma Scale (GCS) less than or equal to 8, on admission. RESULTS: We verified that heart rate, cardiac output, and oxygen delivery index (DO2I) decreased with decreasing core temperature. We recognized that depressed cardiac index (CI) was attributed to bradycardia, dehydration, and increased systemic vascular resistance index (SVRI) upon initiation of hypothermia. CONCLUSION: Although the hypothermia has a therapeutic role in severe brain damage patients, we have to carry out this therapy while maintaining their cardiac output using multimodality monitoring devices during hypothermia period. Medknow Publications & Media Pvt Ltd 2012 /pmc/articles/PMC3410162/ /pubmed/22870153 http://dx.doi.org/10.4103/1793-5482.98645 Text en Copyright: © Asian Journal of Neurosurgery http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Honda, Mitsuru
Yokota, Kyosuke
Ichibayashi, Ryo
Yoshihara, Katsunori
Masuda, Hiroyuki
Uekusa, Hiroyuki
Seiki, Yoshikatsu
Nomoto, Jun
Nagao, Takeki
Kishi, Taichi
Sase, Shigeru
The study of systemic general circulation disturbance during the initiation of therapeutic hypothermia: Pit fall of hypothermia
title The study of systemic general circulation disturbance during the initiation of therapeutic hypothermia: Pit fall of hypothermia
title_full The study of systemic general circulation disturbance during the initiation of therapeutic hypothermia: Pit fall of hypothermia
title_fullStr The study of systemic general circulation disturbance during the initiation of therapeutic hypothermia: Pit fall of hypothermia
title_full_unstemmed The study of systemic general circulation disturbance during the initiation of therapeutic hypothermia: Pit fall of hypothermia
title_short The study of systemic general circulation disturbance during the initiation of therapeutic hypothermia: Pit fall of hypothermia
title_sort study of systemic general circulation disturbance during the initiation of therapeutic hypothermia: pit fall of hypothermia
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3410162/
https://www.ncbi.nlm.nih.gov/pubmed/22870153
http://dx.doi.org/10.4103/1793-5482.98645
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