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Changing pattern of substance abuse in patients attending a de-addiction centre in north India (1978-2008)

BACKGROUND & OBJECTIVES: The patterns of abused psychoactive substances change over time, and it is important to document such changes. The present retrospective study was carried out to document these changes in patients registered in a de-addiction centre in north India over three decades. MET...

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Autores principales: Basu, Debasish, Aggarwal, Munish, Das, Partha Pratim, Mattoo, Surendra K., Kulhara, Parmanand, Varma, Vijoy K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3410210/
https://www.ncbi.nlm.nih.gov/pubmed/22825602
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author Basu, Debasish
Aggarwal, Munish
Das, Partha Pratim
Mattoo, Surendra K.
Kulhara, Parmanand
Varma, Vijoy K.
author_facet Basu, Debasish
Aggarwal, Munish
Das, Partha Pratim
Mattoo, Surendra K.
Kulhara, Parmanand
Varma, Vijoy K.
author_sort Basu, Debasish
collection PubMed
description BACKGROUND & OBJECTIVES: The patterns of abused psychoactive substances change over time, and it is important to document such changes. The present retrospective study was carried out to document these changes in patients registered in a de-addiction centre in north India over three decades. METHODS: Case notes of all patients registered in the centre from September 1978 till December 31, 2008 were reviewed. Comparisons were made among three decades (1978-1988, 1989-1998, and 1999-2008). RESULTS: The number of registered subjects increased eight-fold over the decades, and age of the subjects presenting for the treatment decreased. The percentages of subjects presenting for the treatment with opioid dependence were 36.8 per cent (n=204), 42.9 per cent (n=809) and 53.2 per cent (n=2219), respectively for the three decades (P<0.001). The proportion of subjects using natural opioids decreased over the three decades (47.4, 26.5 and 18.3%; P<0.001), with a concomitant emergence and/or increase of newer and prescription opioids such as buprenorphine, codeine and dextropropoxyphene. Dependence on tobacco and sedative-hypnotics also increased, and inhalant abuse was reported especially in the third decade. Polysubstance dependence increased significantly over the decades (P<0.001). INTERPRETATION & CONCLUSIONS: Our results showed major shifts in the patterns of substance abuse in clinic-attending patients in north India over the three decades from 1978 till 2008. These have important implications for all the stakeholders concerned with combating the challenge of psychoactive substance abuse in our society.
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spelling pubmed-34102102012-08-06 Changing pattern of substance abuse in patients attending a de-addiction centre in north India (1978-2008) Basu, Debasish Aggarwal, Munish Das, Partha Pratim Mattoo, Surendra K. Kulhara, Parmanand Varma, Vijoy K. Indian J Med Res Original Article BACKGROUND & OBJECTIVES: The patterns of abused psychoactive substances change over time, and it is important to document such changes. The present retrospective study was carried out to document these changes in patients registered in a de-addiction centre in north India over three decades. METHODS: Case notes of all patients registered in the centre from September 1978 till December 31, 2008 were reviewed. Comparisons were made among three decades (1978-1988, 1989-1998, and 1999-2008). RESULTS: The number of registered subjects increased eight-fold over the decades, and age of the subjects presenting for the treatment decreased. The percentages of subjects presenting for the treatment with opioid dependence were 36.8 per cent (n=204), 42.9 per cent (n=809) and 53.2 per cent (n=2219), respectively for the three decades (P<0.001). The proportion of subjects using natural opioids decreased over the three decades (47.4, 26.5 and 18.3%; P<0.001), with a concomitant emergence and/or increase of newer and prescription opioids such as buprenorphine, codeine and dextropropoxyphene. Dependence on tobacco and sedative-hypnotics also increased, and inhalant abuse was reported especially in the third decade. Polysubstance dependence increased significantly over the decades (P<0.001). INTERPRETATION & CONCLUSIONS: Our results showed major shifts in the patterns of substance abuse in clinic-attending patients in north India over the three decades from 1978 till 2008. These have important implications for all the stakeholders concerned with combating the challenge of psychoactive substance abuse in our society. Medknow Publications & Media Pvt Ltd 2012-06 /pmc/articles/PMC3410210/ /pubmed/22825602 Text en Copyright: © The Indian Journal of Medical Research http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Basu, Debasish
Aggarwal, Munish
Das, Partha Pratim
Mattoo, Surendra K.
Kulhara, Parmanand
Varma, Vijoy K.
Changing pattern of substance abuse in patients attending a de-addiction centre in north India (1978-2008)
title Changing pattern of substance abuse in patients attending a de-addiction centre in north India (1978-2008)
title_full Changing pattern of substance abuse in patients attending a de-addiction centre in north India (1978-2008)
title_fullStr Changing pattern of substance abuse in patients attending a de-addiction centre in north India (1978-2008)
title_full_unstemmed Changing pattern of substance abuse in patients attending a de-addiction centre in north India (1978-2008)
title_short Changing pattern of substance abuse in patients attending a de-addiction centre in north India (1978-2008)
title_sort changing pattern of substance abuse in patients attending a de-addiction centre in north india (1978-2008)
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3410210/
https://www.ncbi.nlm.nih.gov/pubmed/22825602
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