MUTYH-associated polyposis (MAP), the syndrome implicating base excision repair in inherited predisposition to colorectal tumors

In 2002, Al-Tassan and co-workers described for the first time a recessive form of inherited polyposis associated with germline mutations of MUTYH, a gene encoding a base excision repair (BER) protein that counteracts the DNA damage induced by the oxidative stress. MUTYH-associated polyposis (MAP) i...

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Detalles Bibliográficos
Autores principales: Venesio, Tiziana, Balsamo, Antonella, D'Agostino, Vito G., Ranzani, Guglielmina N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2012
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3410368/
https://www.ncbi.nlm.nih.gov/pubmed/22876359
http://dx.doi.org/10.3389/fonc.2012.00083

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