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Sds22 and Repo-Man stabilize chromosome segregation by counteracting Aurora B on anaphase kinetochores
During mitotic spindle assembly, Aurora B kinase is part of an error correction mechanism that detaches microtubules from kinetochores that are under low mechanical tension. During anaphase, however, kinetochore–microtubule attachments must be maintained despite a drop of tension after removal of si...
Autores principales: | Wurzenberger, Claudia, Held, Michael, Lampson, Michael A., Poser, Ina, Hyman, Anthony A., Gerlich, Daniel W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3410419/ https://www.ncbi.nlm.nih.gov/pubmed/22801782 http://dx.doi.org/10.1083/jcb.201112112 |
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