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Intervention of PKC-θ as an immunosuppressive regimen
PKC-θ is selectively enriched in T cells and specifically translocates to immunological synapse where it mediates critical T cell receptor signals required for T cell activation, differentiation, and survival. T cells deficient in PKC-θ are defective in their ability to differentiate into inflammato...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Research Foundation
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3410430/ https://www.ncbi.nlm.nih.gov/pubmed/22876242 http://dx.doi.org/10.3389/fimmu.2012.00225 |