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Effect of Arthritic Synovial Fluids on the Expression of Immunomodulatory Factors by Mesenchymal Stem Cells: An Explorative in vitro Study
Background: In diseased joints, the catabolic environment results in progressive joint damage. Mesenchymal stem cells (MSCs) can have immunomodulatory effects by secreting anti-inflammatory factors. To exert these effects, MSCs need to be triggered by pro-inflammatory cytokines. To explore the poten...
Autores principales: | Leijs, Maarten J. C., van Buul, Gerben M., Lubberts, Erik, Bos, Pieter K., Verhaar, Jan A. N., Hoogduijn, Martin J., van Osch, Gerjo J. V. M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Research Foundation
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3410447/ https://www.ncbi.nlm.nih.gov/pubmed/22876244 http://dx.doi.org/10.3389/fimmu.2012.00231 |
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