Cargando…

Rapid Testing of Gene-Gene Interactions in Genome-Wide Association Studies of Binary and Quantitative Phenotypes

Genome-wide association (GWA) studies have been extremely successful in identifying novel loci contributing effects to a wide range of complex human traits. However, despite this success, the joint marginal effects of these loci account for only a small proportion of the heritability of these traits...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bhattacharya, Kanishka, McCarthy, Mark I, Morris, Andrew P
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Wiley Subscription Services, Inc., A Wiley Company 2011
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3410530/ https://www.ncbi.nlm.nih.gov/pubmed/21948692 http://dx.doi.org/10.1002/gepi.20629

Ejemplares similares

Identifying and exploiting gene-pathway interactions from RNA-seq data for binary phenotype
por: Shao, Fang, et al.
Publicado: (2019)

Integrating binary traits with quantitative phenotypes for association mapping of multivariate phenotypes
por: Mukhopadhyay, Indranil, et al.
Publicado: (2011)

Kernel-based gene–environment interaction tests for rare variants with multiple quantitative phenotypes
por: Jin, Xiaoqin, et al.
Publicado: (2022)

Testing Gene-Gene Interactions Based on a Neighborhood Perspective in Genome-wide Association Studies
por: Guo, Yingjie, et al.
Publicado: (2021)

Genome-Wide Search for Gene-Gene Interactions in Colorectal Cancer
por: Jiao, Shuo, et al.
Publicado: (2012)

Gene-Based Testing of Interactions in Association Studies of Quantitative Traits
por: Ma, Li, et al.
Publicado: (2013)

A Novel Test for Gene-Ancestry Interactions in Genome-Wide Association Data
por: Davies, Joanna L., et al.
Publicado: (2012)

Gene-Based Testing of Interactions Using XGBoost in Genome-Wide Association Studies
por: Guo, Yingjie, et al.
Publicado: (2021)

GWGGI: software for genome-wide gene-gene interaction analysis
por: Wei, Changshuai, et al.
Publicado: (2014)

Gene-environment interaction tests for family studies with quantitative phenotypes: A review and extension to longitudinal measures
por: Moreno-Macias, Hortensia, et al.
Publicado: (2010)

High-throughput and quantitative genome-wide messenger RNA sequencing for molecular phenotyping
por: Collins, John E., et al.
Publicado: (2015)

Genome-wide mapping of gene-microbe interactions in the murine lung microbiota based on quantitative microbial profiling
por: Chung, C. J., et al.
Publicado: (2023)

Genome-wide pathway-based quantitative multiple phenotypes analysis
por: Deng, Yamin, et al.
Publicado: (2020)

Genome-Wide Gene-Environment Interaction Analysis Using Set-Based Association Tests
por: Lin, Wan-Yu, et al.
Publicado: (2019)

Integrated Analysis of Gene Expression Differences in Twins Discordant for Disease and Binary Phenotypes
por: Tangirala, Sivateja, et al.
Publicado: (2018)

Artificial neural networks for linkage analysis of quantitative gene expression phenotypes and evaluation of gene × gene interactions
por: Liu, Ying, et al.
Publicado: (2007)

Genome wide association studies in presence of misclassified binary responses
por: Smith, Shannon, et al.
Publicado: (2013)

Large-Scale Analyses Provide No Evidence for Gene-Gene Interactions Influencing Type 2 Diabetes Risk
por: Nag, Abhishek, et al.
Publicado: (2020)

Robust Gene-Gene Interaction Analysis in Genome Wide Association Studies
por: Kim, Yongkang, et al.
Publicado: (2015)

Incorporating biological knowledge in the search for gene × gene interaction in genome-wide association studies
por: Manning, Alisa K, et al.
Publicado: (2009)

Genome-wide assessment of gene-by-smoking interactions in COPD
por: Park, Boram, et al.
Publicado: (2018)

Interacting binaries
por: Shore, S N, et al.
Publicado: (1994)

Rapid and efficient genome-wide characterization of Xanthomonas TAL effector genes
por: Yu, Yan-Hua, et al.
Publicado: (2015)

Using Machine Learning to Predict Obesity Based on Genome-Wide and Epigenome-Wide Gene–Gene and Gene–Diet Interactions
por: Lee, Yu-Chi, et al.
Publicado: (2022)

Guidance for the utility of linear models in meta-analysis of genetic association studies of binary phenotypes
por: Cook, James P, et al.
Publicado: (2017)

Leveraging local ancestry to detect gene-gene interactions in genome-wide data
por: Aschard, Hugues, et al.
Publicado: (2015)

Stochastic model search with binary outcomes for genome-wide association studies
por: Russu, Alberto, et al.
Publicado: (2012)

Genome-Wide Diet-Gene Interaction Analyses for Risk of Colorectal Cancer
por: Figueiredo, Jane C., et al.
Publicado: (2014)

A comparison of case-only designs for detecting gene × gene interaction in rheumatoid arthritis using genome-wide case-control data in Genetic Analysis Workshop 16
por: Clarke, Geraldine M, et al.
Publicado: (2009)

Genome-wide analysis of E. coli cell-gene interactions
por: Cardinale, S., et al.
Publicado: (2017)

NMD Microarray Analysis for Rapid Genome-Wide Screen of Mutated Genes in Cancer
por: Wolf, Maija, et al.
Publicado: (2005)

Rapid scoring of genes in microbial pan-genome-wide association studies with Scoary
por: Brynildsrud, Ola, et al.
Publicado: (2016)

Multivariate phenotype analysis enables genome-wide inference of mammalian gene function
por: Nicholson, George, et al.
Publicado: (2022)

The choice of null distributions for detecting gene-gene interactions in genome-wide association studies
por: Yang, Can, et al.
Publicado: (2011)

Network Graph Analysis of Gene-Gene Interactions in Genome-Wide Association Study Data
por: Lee, Sungyoung, et al.
Publicado: (2012)

IGENT: efficient entropy based algorithm for genome-wide gene-gene interaction analysis
por: Kwon, Min-Seok, et al.
Publicado: (2014)

Genome-wide identification of key modulators of gene-gene interaction networks in breast cancer
por: Chiu, Yu-Chiao, et al.
Publicado: (2017)

Interacting binary stars
por: Sahade, Jorge, et al.
Publicado: (1978)

A Flexible Approach for the Analysis of Rare Variants Allowing for a Mixture of Effects on Binary or Quantitative Traits
por: Clarke, Geraldine M., et al.
Publicado: (2013)

Genome-Wide Identification of Reference Genes for Reverse-Transcription Quantitative PCR in Goat Rumen
por: Zhao, Juan, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_e1eoolkiekt73d1v041mt6nsbo