GABA(B)-mediated rescue of altered excitatory–inhibitory balance, gamma synchrony and behavioral deficits following constitutive NMDAR-hypofunction

Reduced N-methyl-D-aspartate-receptor (NMDAR) signaling has been associated with schizophrenia, autism and intellectual disability. NMDAR-hypofunction is thought to contribute to social, cognitive and gamma (30–80 Hz) oscillatory abnormalities, phenotypes common to these disorders. However, circuit-...

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Detalles Bibliográficos
Autores principales: Gandal, M J, Sisti, J, Klook, K, Ortinski, P I, Leitman, V, Liang, Y, Thieu, T, Anderson, R, Pierce, R C, Jonak, G, Gur, R E, Carlson, G, Siegel, S J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3410621/
https://www.ncbi.nlm.nih.gov/pubmed/22806213
http://dx.doi.org/10.1038/tp.2012.69

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