The tyrosine phosphatase STEP: implications in schizophrenia and the molecular mechanism underlying antipsychotic medications

Glutamatergic signaling through N-methyl-D-aspartate receptors (NMDARs) is required for synaptic plasticity. Disruptions in glutamatergic signaling are proposed to contribute to the behavioral and cognitive deficits observed in schizophrenia (SZ). One possible source of compromised glutamatergic fun...

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Detalles Bibliográficos
Autores principales: Carty, N C, Xu, J, Kurup, P, Brouillette, J, Goebel-Goody, S M, Austin, D R, Yuan, P, Chen, G, Correa, P R, Haroutunian, V, Pittenger, C, Lombroso, P J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3410627/
https://www.ncbi.nlm.nih.gov/pubmed/22781170
http://dx.doi.org/10.1038/tp.2012.63

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