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The influence of polygenic risk for bipolar disorder on neural activation assessed using fMRI

Genome-wide association studies (GWAS) have demonstrated a significant polygenic contribution to bipolar disorder (BD) where disease risk is determined by the summation of many alleles of small individual magnitude. Modelling polygenic risk scores may be a powerful way of identifying disrupted brain...

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Detalles Bibliográficos
Autores principales: Whalley, H C, Papmeyer, M, Sprooten, E, Romaniuk, L, Blackwood, D H, Glahn, D C, Hall, J, Lawrie, S M, Sussmann, Je, McIntosh, A M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3410628/
https://www.ncbi.nlm.nih.gov/pubmed/22760554
http://dx.doi.org/10.1038/tp.2012.60