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Potential role of odanacatib in the treatment of osteoporosis
Cathepsin K is a key enzyme involved in the degradation of organic bone matrix by osteoclasts. Inhibition of bone resorption observed in human and animal models deficient for cathepsin K has identified this enzyme as a suitable target for intervention by small molecules with the potential to be used...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Dove Medical Press
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3410681/ https://www.ncbi.nlm.nih.gov/pubmed/22866001 http://dx.doi.org/10.2147/CIA.S26729 |