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Disruption of the folate pathway in zebrafish causes developmental defects

BACKGROUND: Folic acid supplementation reduces the risk of neural tube defects and congenital heart defects. The biological mechanisms through which folate prevents birth defects are not well understood. We explore the use of zebrafish as a model system to investigate the role of folate metabolism d...

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Detalles Bibliográficos
Autores principales:	Lee, Marina S, Bonner, Jenna R, Bernard, David J, Sanchez, Erica L, Sause, Eric T, Prentice, R Reid, Burgess, Shawn M, Brody, Lawrence C
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3410756/ https://www.ncbi.nlm.nih.gov/pubmed/22480165 http://dx.doi.org/10.1186/1471-213X-12-12

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