Cargando…

IOP induces upregulation of GFAP and MHC-II and microglia reactivity in mice retina contralateral to experimental glaucoma

BACKGROUND: Ocular hypertension is a major risk factor for glaucoma, a neurodegenerative disease characterized by an irreversible decrease in ganglion cells and their axons. Macroglial and microglial cells appear to play an important role in the pathogenic mechanisms of the disease. Here, we study t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gallego, Beatriz I, Salazar, Juan J, de Hoz, Rosa, Rojas, Blanca, Ramírez, Ana I, Salinas-Navarro, Manuel, Ortín-Martínez, Arturo, Valiente-Soriano, Francisco J, Avilés-Trigueros, Marcelino, Villegas-Perez, Maria P, Vidal-Sanz, Manuel, Triviño, Alberto, Ramírez, Jose M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3410794/ https://www.ncbi.nlm.nih.gov/pubmed/22583833 http://dx.doi.org/10.1186/1742-2094-9-92

Ejemplares similares

Microglia in mouse retina contralateral to experimental glaucoma exhibit multiple signs of activation in all retinal layers
por: Rojas, Blanca, et al.
Publicado: (2014)

Rod-Like Microglia Are Restricted to Eyes with Laser-Induced Ocular Hypertension but Absent from the Microglial Changes in the Contralateral Untreated Eye
por: de Hoz, Rosa, et al.
Publicado: (2013)

Functional and morphological effects of laser-induced ocular hypertension in retinas of adult albino Swiss mice
por: Salinas-Navarro, Manuel, et al.
Publicado: (2009)

Alpha retinal ganglion cells in pigmented mice retina: number and distribution
por: Gallego-Ortega, Alejandro, et al.
Publicado: (2022)

Time course of bilateral microglial activation in a mouse model of laser-induced glaucoma
por: Ramírez, Ana I., et al.
Publicado: (2020)

Automatic Counting of Microglial Cells in Healthy and Glaucomatous Mouse Retinas
por: de Gracia, Pablo, et al.
Publicado: (2015)

Effects of Ocular Hypertension in the Visual System of Pigmented Mice
por: Valiente-Soriano, Francisco J., et al.
Publicado: (2015)

7,8-Dihydroxiflavone Maintains Retinal Functionality and Protects Various Types of RGCs in Adult Rats with Optic Nerve Transection
por: Gallego-Ortega, Alejandro, et al.
Publicado: (2021)

Shared and Differential Retinal Responses against Optic Nerve Injury and Ocular Hypertension
por: Vidal-Sanz, Manuel, et al.
Publicado: (2017)

Distribution of melanopsin positive neurons in pigmented and albino mice: evidence for melanopsin interneurons in the mouse retina
por: Valiente-Soriano, Francisco J., et al.
Publicado: (2014)

Neuronal Death in the Contralateral Un-Injured Retina after Unilateral Axotomy: Role of Microglial Cells
por: Lucas-Ruiz, Fernando, et al.
Publicado: (2019)

Tracing the retina to analyze the integrity and phagocytic capacity of the retinal pigment epithelium
por: Valiente-Soriano, Francisco J., et al.
Publicado: (2020)

Retinal Molecular Changes Are Associated with Neuroinflammation and Loss of RGCs in an Experimental Model of Glaucoma
por: Fernández-Albarral, José A., et al.
Publicado: (2021)

Retinal Macroglial Responses in Health and Disease
por: de Hoz, Rosa, et al.
Publicado: (2016)

A Chronic Ocular-Hypertensive Rat Model induced by Injection of the Sclerosant Agent Polidocanol in the Aqueous Humor Outflow Pathway
por: Blanco, Román, et al.
Publicado: (2019)

Animal Models of LED-Induced Phototoxicity. Short- and Long-Term In Vivo and Ex Vivo Retinal Alterations
por: Miralles de Imperial-Ollero, Juan A., et al.
Publicado: (2021)

Axonal Injuries Cast Long Shadows: Long Term Glial Activation in Injured and Contralateral Retinas after Unilateral Axotomy
por: González-Riquelme, María José, et al.
Publicado: (2021)

Short and long term axotomy-induced ERG changes in albino and pigmented rats
por: Alarcón-Martínez, Luis, et al.
Publicado: (2009)

Neuroprotective Effects of Low-Dose Statins in the Retinal Ultrastructure of Hypercholesterolemic Rabbits
por: Fernández-Navarro, Judith, et al.
Publicado: (2016)

Selective laser trabeculoplasty reduces mean IOP and IOP variation in normal tension glaucoma patients
por: El Mallah, Mohammed K, et al.
Publicado: (2010)

Ectopic insert-dependent neuronal expression of GFAP promoter-driven AAV constructs in adult mouse retina
por: Le, Nguyet, et al.
Publicado: (2022)

GFAP at 50
por: Messing, Albee, et al.
Publicado: (2020)

Retinal compensatory changes after light damage in albino mice
por: Montalbán-Soler, Luis, et al.
Publicado: (2012)

Detecting IOP Fluctuations in Glaucoma Patients
por: Nuyen, Brenda, et al.
Publicado: (2016)

Significance of non-intraocular pressure (IOP)-related factors particularly in normal tension glaucoma: Looking beyond IOP
por: Dinakaran, Shoruba, et al.
Publicado: (2022)

Implanted Microsensor Continuous IOP Telemetry Suggests Gaze and Eyelid Closure Effects on IOP—A Preliminary Study
por: van den Bosch, Jacqueline J. O. N., et al.
Publicado: (2021)

IOP, IOP Transient Impulse, Ocular Perfusion Pressure, and Mean Arterial Pressure Relationships in Nonhuman Primates Instrumented With Telemetry
por: Markert, John E., et al.
Publicado: (2018)

Regulation of GFAP Expression
por: Brenner, Michael, et al.
Publicado: (2021)

Pigment Epithelium-Derived Factor (PEDF) Fragments Prevent Mouse Cone Photoreceptor Cell Loss Induced by Focal Phototoxicity In Vivo
por: Valiente-Soriano, Francisco J., et al.
Publicado: (2020)

Ly6c as a New Marker of Mouse Blood Vessels: Qualitative and Quantitative Analyses on Intact and Ischemic Retinas
por: Martínez-Carmona, Marina, et al.
Publicado: (2021)

The Magnitude and Time Course of IOP Change in Response to Body Position Change in Nonhuman Primates Measured Using Continuous IOP Telemetry
por: Turner, Daniel C., et al.
Publicado: (2017)

“Super p53” Mice Display Retinal Astroglial Changes
por: Salazar, Juan J., et al.
Publicado: (2013)

Topical Brimonidine or Intravitreal BDNF, CNTF, or bFGF Protect Cones Against Phototoxicity
por: Valiente-Soriano, Francisco J., et al.
Publicado: (2019)

The retina of the lab rat: focus on retinal ganglion cells and photoreceptors
por: Galindo-Romero, Caridad, et al.
Publicado: (2022)

Ophthalmologic Psychophysical Tests Support OCT Findings in Mild Alzheimer's Disease
por: Salobrar-Garcia, Elena, et al.
Publicado: (2015)

A Review of Intraocular Pressure (IOP) and Axial Myopia
por: Zhang, Dongyan, et al.
Publicado: (2022)

Optic Nerve Head Gene Transcription Sequelae to a Single Elevated IOP Exposure Provides Insights Into Known Responses to Chronically Elevated IOP
por: Lozano, Diana C., et al.
Publicado: (2023)

Measuring accurate IOPs: Does correction factor help or hurt?
por: Gunvant, Pinakin, et al.
Publicado: (2010)

Genomic Locus Modulating IOP in the BXD RI Mouse Strains
por: King, Rebecca, et al.
Publicado: (2018)

Correlation of IOP with Corneal Acoustic Impedance in Porcine Eye Model
por: Zhang, Jun, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_up1jqmmp7re3c8tfkutqslimf6