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Up-regulation of microglial cathepsin C expression and activity in lipopolysaccharide-induced neuroinflammation
BACKGROUND: Cathepsin C (Cat C) functions as a central coordinator for activation of many serine proteases in inflammatory cells. It has been recognized that Cat C is responsible for neutrophil recruitment and production of chemokines and cytokines in many inflammatory diseases. However, Cat C expre...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3410810/ https://www.ncbi.nlm.nih.gov/pubmed/22607609 http://dx.doi.org/10.1186/1742-2094-9-96 |