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Structural Analysis of Specific Metal Chelating Inhibitor Binding to the Endonuclease Domain of Influenza pH1N1 (2009) Polymerase

It is generally recognised that novel antiviral drugs, less prone to resistance, would be a desirable alternative to current drug options in order to be able to treat potentially serious influenza infections. The viral polymerase, which performs transcription and replication of the RNA genome, is an...

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Detalles Bibliográficos
Autores principales:	Kowalinski, Eva, Zubieta, Chloe, Wolkerstorfer, Andrea, Szolar, Oliver H. J., Ruigrok, Rob W. H., Cusack, Stephen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3410856/ https://www.ncbi.nlm.nih.gov/pubmed/22876177 http://dx.doi.org/10.1371/journal.ppat.1002831

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