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Exon Level Transcriptomic Profiling of HIV-1-Infected CD4(+) T Cells Reveals Virus-Induced Genes and Host Environment Favorable for Viral Replication
HIV-1 is extremely specialized since, even amongst CD4(+) T lymphocytes (its major natural reservoir in peripheral blood), the virus productively infects only a small proportion of cells under an activated state. As the percentage of HIV-1-infected cells is very low, most studies have so far failed...
Autores principales: | Imbeault, Michaël, Giguère, Katia, Ouellet, Michel, Tremblay, Michel J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3410884/ https://www.ncbi.nlm.nih.gov/pubmed/22876188 http://dx.doi.org/10.1371/journal.ppat.1002861 |
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