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Dissecting and Circumventing the Requirement for RAM in CSL-Dependent Notch Signaling
The Notch signaling pathway is an intercellular communication network vital to metazoan development. Notch activation leads to the nuclear localization of the intracellular portion (NICD) of the Notch receptor. Once in the nucleus, NICD binds the transcription factor CSL through a bivalent interacti...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3410904/ https://www.ncbi.nlm.nih.gov/pubmed/22876274 http://dx.doi.org/10.1371/journal.pone.0039093 |