Hypothesis-Based Analysis of Gene-Gene Interactions and Risk of Myocardial Infarction

The genetic loci that have been found by genome-wide association studies to modulate risk of coronary heart disease explain only a fraction of its total variance, and gene-gene interactions have been proposed as a potential source of the remaining heritability. Given the potentially large testing bu...

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Detalles Bibliográficos
Autores principales: Lucas, Gavin, Lluís-Ganella, Carla, Subirana, Isaac, Musameh, Muntaser D., Gonzalez, Juan Ramon, Nelson, Christopher P., Sentí, Mariano, Schwartz, Stephen M., Siscovick, David, O’Donnell, Christopher J., Melander, Olle, Salomaa, Veikko, Purcell, Shaun, Altshuler, David, Samani, Nilesh J., Kathiresan, Sekar, Elosua, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3410908/
https://www.ncbi.nlm.nih.gov/pubmed/22876292
http://dx.doi.org/10.1371/journal.pone.0041730

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