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Antitumor Activity of Emodin against Pancreatic Cancer Depends on Its Dual Role: Promotion of Apoptosis and Suppression of Angiogenesis
BACKGROUND: Emodin has been showed to induce apoptosis of pancreatic cancer cells and inhibit tumor growth in our previous studies. This study was designed to investigate whether emodin could inhibit the angiogenesis of pancreatic cancer tissues and its mechanism. METHODOLOGY/PRINCIPAL FINDING: In a...
Autores principales: | Lin, Sheng-Zhang, Wei, Wei-Tian, Chen, Hui, Chen, Kang-Jie, Tong, Hong-Fei, Wang, Zhao-Hong, Ni, Zhong-Lin, Liu, Hai-Bin, Guo, Hong-Chun, Liu, Dian-Lei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3410916/ https://www.ncbi.nlm.nih.gov/pubmed/22876305 http://dx.doi.org/10.1371/journal.pone.0042146 |
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