Cargando…
Astrocyte Inositol Triphosphate Receptor Type 2 and Cytosolic Phospholipase A(2) Alpha Regulate Arteriole Responses in Mouse Neocortical Brain Slices
Functional hyperemia of the cerebral vascular system matches regional blood flow to the metabolic demands of the brain. One current model of neurovascular control holds that glutamate released by neurons activates group I metabotropic glutamate receptors (mGluRs) on astrocytes, resulting in the prod...
Autores principales: | He, Lihua, Linden, David J., Sapirstein, Adam |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3410924/ https://www.ncbi.nlm.nih.gov/pubmed/22876307 http://dx.doi.org/10.1371/journal.pone.0042194 |
Ejemplares similares
-
Cytosolic phospholipase A(2 )alpha amplifies early cyclooxygenase-2 expression, oxidative stress and MAP kinase phosphorylation after cerebral ischemia in mice
por: Kishimoto, Koji, et al.
Publicado: (2010) -
Dynamic Inositol Trisphosphate-mediated Calcium Signals within Astrocytic Endfeet Underlie Vasodilation of Cerebral Arterioles
por: Straub, Stephen V., et al.
Publicado: (2006) -
Assaying activity-dependent arteriole and capillary responses in brain slices
por: Bojovic, Danica, et al.
Publicado: (2022) -
Regulatory role of cytosolic phospholipase A(2) alpha in the induction of CD40 in microglia
por: Malada-Edelstein, Yafa Fetfet, et al.
Publicado: (2017) -
Astrocytes mediate neurovascular signaling to capillary pericytes but not to arterioles
por: Mishra, Anusha, et al.
Publicado: (2016)