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Accelerated simulation of unfolding and refolding of a large single chain globular protein
We have developed novel strategies for contracting simulation times in protein dynamics that enable us to study a complex protein with molecular weight in excess of 34 kDa. Starting from a crystal structure, we produce unfolded and then refolded states for the protein. We then compare these quantita...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3411113/ https://www.ncbi.nlm.nih.gov/pubmed/22870389 http://dx.doi.org/10.1098/rsob.120087 |