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Forward Genetic Analysis to Identify Determinants of Dopamine Signaling in Caenorhabditis elegans Using Swimming-Induced Paralysis

Disrupted dopamine (DA) signaling is believed to contribute to the core features of multiple neuropsychiatric and neurodegenerative disorders. Essential features of DA neurotransmission are conserved in the nematode Caenorhabditis elegans, providing us with an opportunity to implement forward geneti...

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Detalles Bibliográficos
Autores principales: Hardaway, J. Andrew, Hardie, Shannon L., Whitaker, Sarah M., Baas, Sarah R., Zhang, Bing, Bermingham, Daniel P., Lichtenstein, Ariana J., Blakely, Randy D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3411251/
https://www.ncbi.nlm.nih.gov/pubmed/22908044
http://dx.doi.org/10.1534/g3.112.003533