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Forward Genetic Analysis to Identify Determinants of Dopamine Signaling in Caenorhabditis elegans Using Swimming-Induced Paralysis
Disrupted dopamine (DA) signaling is believed to contribute to the core features of multiple neuropsychiatric and neurodegenerative disorders. Essential features of DA neurotransmission are conserved in the nematode Caenorhabditis elegans, providing us with an opportunity to implement forward geneti...
Autores principales: | Hardaway, J. Andrew, Hardie, Shannon L., Whitaker, Sarah M., Baas, Sarah R., Zhang, Bing, Bermingham, Daniel P., Lichtenstein, Ariana J., Blakely, Randy D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Genetics Society of America
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3411251/ https://www.ncbi.nlm.nih.gov/pubmed/22908044 http://dx.doi.org/10.1534/g3.112.003533 |
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