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Prevalence Rate and Functional Status of Cerebellar Ataxia in Korea

Cerebellar ataxia (hereinafter referred to as CA) designate a group of neurodegenerative disorders. CA is distinguished into a group of hereditary and non-hereditary disorders. CA shows clinically progressive features and accompanies various neurological abnormalities. However, there are very few st...

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Autores principales: Joo, Byung-Euk, Lee, Chan-Nyoung, Park, Kun-Woo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3411295/
https://www.ncbi.nlm.nih.gov/pubmed/22144210
http://dx.doi.org/10.1007/s12311-011-0332-8
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author Joo, Byung-Euk
Lee, Chan-Nyoung
Park, Kun-Woo
author_facet Joo, Byung-Euk
Lee, Chan-Nyoung
Park, Kun-Woo
author_sort Joo, Byung-Euk
collection PubMed
description Cerebellar ataxia (hereinafter referred to as CA) designate a group of neurodegenerative disorders. CA is distinguished into a group of hereditary and non-hereditary disorders. CA shows clinically progressive features and accompanies various neurological abnormalities. However, there are very few studies and case reports in Korean patients. To estimate the prevalence rate and current status of the CA patients in Korea, we used data from the Health Insurance Review and Assessment Service (HIRAS) and from the National Health Insurance Corporation. To evaluate the functional status of CA patient in Korea, we conducted a simple random sampling among the 500 members of Korea Ataxia Society registered on its homepage. We evaluated the functional status and degree of disturbance to their everyday life with modified Rankin scales and Barthel ADL index. Using the data from HIRAS, we could estimate the prevalence rate of CA patients in Korea as 8.29 patients/100,000 persons. The prevalence rate of hereditary and non-hereditary cerebellar ataxia was 4.99 patients/100,000 persons and 3.30 patients/100,000 persons, respectively. Data on rare intractable diseases reported by the Korean Centers for Disease Control and Prevention in 2006 suggested that the number of CA patients who have visited medical institutes was almost doubled for the 2-year period. The medical expense and hospital stay also increased 4.5- and 3-fold, respectively. After severity evaluation with modified Rankin scales and Barthel ADL index, we found that most CA patients in Korea have ataxia-related difficulties in their everyday life.
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spelling pubmed-34112952012-08-23 Prevalence Rate and Functional Status of Cerebellar Ataxia in Korea Joo, Byung-Euk Lee, Chan-Nyoung Park, Kun-Woo Cerebellum Original Paper Cerebellar ataxia (hereinafter referred to as CA) designate a group of neurodegenerative disorders. CA is distinguished into a group of hereditary and non-hereditary disorders. CA shows clinically progressive features and accompanies various neurological abnormalities. However, there are very few studies and case reports in Korean patients. To estimate the prevalence rate and current status of the CA patients in Korea, we used data from the Health Insurance Review and Assessment Service (HIRAS) and from the National Health Insurance Corporation. To evaluate the functional status of CA patient in Korea, we conducted a simple random sampling among the 500 members of Korea Ataxia Society registered on its homepage. We evaluated the functional status and degree of disturbance to their everyday life with modified Rankin scales and Barthel ADL index. Using the data from HIRAS, we could estimate the prevalence rate of CA patients in Korea as 8.29 patients/100,000 persons. The prevalence rate of hereditary and non-hereditary cerebellar ataxia was 4.99 patients/100,000 persons and 3.30 patients/100,000 persons, respectively. Data on rare intractable diseases reported by the Korean Centers for Disease Control and Prevention in 2006 suggested that the number of CA patients who have visited medical institutes was almost doubled for the 2-year period. The medical expense and hospital stay also increased 4.5- and 3-fold, respectively. After severity evaluation with modified Rankin scales and Barthel ADL index, we found that most CA patients in Korea have ataxia-related difficulties in their everyday life. Springer-Verlag 2011-12-06 2012 /pmc/articles/PMC3411295/ /pubmed/22144210 http://dx.doi.org/10.1007/s12311-011-0332-8 Text en © The Author(s) 2011 https://creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited.
spellingShingle Original Paper
Joo, Byung-Euk
Lee, Chan-Nyoung
Park, Kun-Woo
Prevalence Rate and Functional Status of Cerebellar Ataxia in Korea
title Prevalence Rate and Functional Status of Cerebellar Ataxia in Korea
title_full Prevalence Rate and Functional Status of Cerebellar Ataxia in Korea
title_fullStr Prevalence Rate and Functional Status of Cerebellar Ataxia in Korea
title_full_unstemmed Prevalence Rate and Functional Status of Cerebellar Ataxia in Korea
title_short Prevalence Rate and Functional Status of Cerebellar Ataxia in Korea
title_sort prevalence rate and functional status of cerebellar ataxia in korea
topic Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3411295/
https://www.ncbi.nlm.nih.gov/pubmed/22144210
http://dx.doi.org/10.1007/s12311-011-0332-8
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