Results of a phase-I/II randomized, masked, placebo-controlled trial of recombinant human interleukin-11 (rhIL-11) in the treatment of subjects with active rheumatoid arthritis

Interleukin-11 (IL-11) is a pleiotropic cytokine that regulates the growth and development of hematopoietic stem cells and decreases the proinflammatory mediators of cytokine and nitric oxide production. In animal models of arthritis, treatment with recombinant human IL-11 (rhIL-11) reduces both the...

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Detalles Bibliográficos
Autores principales: Moreland, Larry, Gugliotti, Ron, King, Kevin, Chase, Walter, Weisman, Michael, Greco, Thomas, Fife, Rose, Korn, Joseph, Simms, Robert, Tesser, John, Hillson, Jan, Caldwell, Jacques, Schnitzer, Thomas, Lyons, David, Schwertschlag, Ullrich
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2001
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC34114/
https://www.ncbi.nlm.nih.gov/pubmed/11438043

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