Survivin Is Required for Beta-Cell Mass Expansion in the Pancreatic Duct-Ligated Mouse Model

AIMS/HYPOTHESIS: Pancreatic beta-cell mass expands through adulthood under certain conditions. The related molecular mechanisms are elusive. This study was designed to determine whether surviving (also known as Birc5), which is transiently expressed perinatally in islets, was required for beta-cell...

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Detalles Bibliográficos
Autores principales: Wu, Xiaohong, Zhang, Qinfeng, Wang, Xiaojing, Zhu, Jiayu, Xu, Kuangfeng, Okada, Hitoshi, Wang, Rennian, Woo, Minna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3411579/
https://www.ncbi.nlm.nih.gov/pubmed/22870272
http://dx.doi.org/10.1371/journal.pone.0041976

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