Leptospiral Hemolysins Induce Proinflammatory Cytokines through Toll-Like Receptor 2-and 4-Mediated JNK and NF-κB Signaling Pathways

BACKGROUND: Infection with pathogenic Leptospira species causes serious systemic inflammation in patients. Although a few leptospiral proinflammatory molecules have been identified, Leptospira likely encodes other unidentified strong inflammation stimulators. The pathogenic L. interrogans genome enc...

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Detalles Bibliográficos
Autores principales: Wang, Huan, Wu, Yifei, Ojcius, David M., Yang, X. Frank, Zhang, Chenglin, Ding, Shibiao, Lin, Xu’ai, Yan, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3411626/
https://www.ncbi.nlm.nih.gov/pubmed/22870312
http://dx.doi.org/10.1371/journal.pone.0042266

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3411626/
https://www.ncbi.nlm.nih.gov/pubmed/22870312
http://dx.doi.org/10.1371/journal.pone.0042266

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