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Leptospiral Hemolysins Induce Proinflammatory Cytokines through Toll-Like Receptor 2-and 4-Mediated JNK and NF-κB Signaling Pathways

BACKGROUND: Infection with pathogenic Leptospira species causes serious systemic inflammation in patients. Although a few leptospiral proinflammatory molecules have been identified, Leptospira likely encodes other unidentified strong inflammation stimulators. The pathogenic L. interrogans genome enc...

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Detalles Bibliográficos
Autores principales:	Wang, Huan, Wu, Yifei, Ojcius, David M., Yang, X. Frank, Zhang, Chenglin, Ding, Shibiao, Lin, Xu’ai, Yan, Jie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3411626/ https://www.ncbi.nlm.nih.gov/pubmed/22870312 http://dx.doi.org/10.1371/journal.pone.0042266

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