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A Key Role for the Endothelium in NOD1 Mediated Vascular Inflammation: Comparison to TLR4 Responses
Understanding the mechanisms by which pathogens induce vascular inflammation and dysfunction may reveal novel therapeutic targets in sepsis and related conditions. The intracellular receptor NOD1 recognises peptidoglycan which features in the cell wall of Gram negative and some Gram positive bacteri...
Autores principales: | Gatheral, Timothy, Reed, Daniel M., Moreno, Laura, Gough, Peter J., Votta, Bart J., Sehon, Clark A., Rickard, David J., Bertin, John, Lim, Eric, Nicholson, Andrew G., Mitchell, Jane A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3411636/ https://www.ncbi.nlm.nih.gov/pubmed/22870324 http://dx.doi.org/10.1371/journal.pone.0042386 |
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