Proteomic Profiling of a Mouse Model for Ovarian Granulosa Cell Tumor Identifies VCP as a Highly Sensitive Serum Tumor Marker in Several Human Cancers

The initial aim of this study was to identify novel serum diagnostic markers for the human ovarian granulosa cell tumor (GCT), a tumor that represents up to 5% of all ovarian cancers. To circumvent the paucity of human tissues available for analyses, we used the Ctnnb1 (tm1Mmt/+);Pten (tm1Hwu/tmiHwu...

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Detalles Bibliográficos
Autores principales: Laguë, Marie-Noëlle, Romieu-Mourez, Raphaëlle, Bonneil, Éric, Boyer, Alexandre, Pouletty, Nicolas, Mes-Masson, Anne-Marie, Thibault, Pierre, Nadeau, Marie-Ève, Boerboom, Derek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3411637/
https://www.ncbi.nlm.nih.gov/pubmed/22870330
http://dx.doi.org/10.1371/journal.pone.0042470

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