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SA-4-1BBL Costimulation Inhibits Conversion of Conventional CD4(+) T Cells into CD4(+)FoxP3(+) T Regulatory Cells by Production of IFN-γ

Tumors convert conventional CD4(+) T cells into induced CD4(+)CD25(+)FoxP3(+) T regulatory (iTreg) cells that serve as an effective means of immune evasion. Therefore, the blockade of conventional CD4(+) T cell conversion into iTreg cells represents an attractive target for improving the efficacy of...

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Detalles Bibliográficos
Autores principales:	Madireddi, Shravan, Schabowsky, Rich-Henry, Srivastava, Abhishek K., Sharma, Rajesh K., Yolcu, Esma S., Shirwan, Haval
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3411638/ https://www.ncbi.nlm.nih.gov/pubmed/22870329 http://dx.doi.org/10.1371/journal.pone.0042459

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