HSPB2 Is Dispensable for the Cardiac Hypertrophic Response but Reduces Mitochondrial Energetics following Pressure Overload In Mice

BACKGROUND: CryAB (HspB5) and HspB2, two small heat shock genes located adjacently in the vertebrate genome, are hypothesized to play distinct roles. Mice lacking both cryab and hspb2 (DKO) are viable and exhibit adult-onset degeneration of skeletal muscle but confounding results from independent gr...

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Detalles Bibliográficos
Autores principales: Ishiwata, Takahiro, Orosz, András, Wang, Xiaohui, Mustafi, Soumyajit Banerjee, Pratt, Gregory W., Christians, Elisabeth S., Boudina, Sihem, Abel, E. Dale, Benjamin, Ivor J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3411653/
https://www.ncbi.nlm.nih.gov/pubmed/22870288
http://dx.doi.org/10.1371/journal.pone.0042118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3411653/
https://www.ncbi.nlm.nih.gov/pubmed/22870288
http://dx.doi.org/10.1371/journal.pone.0042118

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