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Leishmania Promastigotes Lack Phosphatidylserine but Bind Annexin V upon Permeabilization or Miltefosine Treatment

The protozoan parasite Leishmania is an intracellular pathogen infecting and replicating inside vertebrate host macrophages. A recent model suggests that promastigote and amastigote forms of the parasite mimic mammalian apoptotic cells by exposing phosphatidylserine (PS) at the cell surface to trigg...

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Detalles Bibliográficos
Autores principales: Weingärtner, Adrien, Kemmer, Gerdi, Müller, Frederic D., Zampieri, Ricardo Andrade, Gonzaga dos Santos, Marcos, Schiller, Jürgen, Pomorski, Thomas Günther
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3411662/
https://www.ncbi.nlm.nih.gov/pubmed/22870283
http://dx.doi.org/10.1371/journal.pone.0042070