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Leishmania Promastigotes Lack Phosphatidylserine but Bind Annexin V upon Permeabilization or Miltefosine Treatment
The protozoan parasite Leishmania is an intracellular pathogen infecting and replicating inside vertebrate host macrophages. A recent model suggests that promastigote and amastigote forms of the parasite mimic mammalian apoptotic cells by exposing phosphatidylserine (PS) at the cell surface to trigg...
Autores principales: | Weingärtner, Adrien, Kemmer, Gerdi, Müller, Frederic D., Zampieri, Ricardo Andrade, Gonzaga dos Santos, Marcos, Schiller, Jürgen, Pomorski, Thomas Günther |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3411662/ https://www.ncbi.nlm.nih.gov/pubmed/22870283 http://dx.doi.org/10.1371/journal.pone.0042070 |
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