Exercise Training Prevents Oxidative Stress and Ubiquitin-Proteasome System Overactivity and Reverse Skeletal Muscle Atrophy in Heart Failure

BACKGROUND: Heart failure (HF) is known to lead to skeletal muscle atrophy and dysfunction. However, intracellular mechanisms underlying HF-induced myopathy are not fully understood. We hypothesized that HF would increase oxidative stress and ubiquitin-proteasome system (UPS) activation in skeletal...

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Detalles Bibliográficos
Autores principales: Cunha, Telma F., Bacurau, Aline V. N., Moreira, Jose B. N., Paixão, Nathalie A., Campos, Juliane C., Ferreira, Julio C. B., Leal, Marcelo L., Negrão, Carlos E., Moriscot, Anselmo S., Wisløff, Ulrik, Brum, Patricia C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3411696/
https://www.ncbi.nlm.nih.gov/pubmed/22870245
http://dx.doi.org/10.1371/journal.pone.0041701

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