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ChIPnorm: A Statistical Method for Normalizing and Identifying Differential Regions in Histone Modification ChIP-seq Libraries

The advent of high-throughput technologies such as ChIP-seq has made possible the study of histone modifications. A problem of particular interest is the identification of regions of the genome where different cell types from the same organism exhibit different patterns of histone enrichment. This p...

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Detalles Bibliográficos
Autores principales: Nair, Nishanth Ulhas, Sahu, Avinash Das, Bucher, Philipp, Moret, Bernard M. E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3411705/
https://www.ncbi.nlm.nih.gov/pubmed/22870189
http://dx.doi.org/10.1371/journal.pone.0039573