Cargando…

Progression of Mouse Skin Carcinogenesis Is Associated with Increased Erα Levels and Is Repressed by a Dominant Negative Form of Erα

Estrogen receptors (ER), namely ERα and ERβ, are hormone-activated transcription factors with an important role in carcinogenesis. In the present study, we aimed at elucidating the implication of ERα in skin cancer, using chemically-induced mouse skin tumours, as well as cell lines representing dist...

Descripción completa

Detalles Bibliográficos
Autores principales:	Logotheti, Stella, Papaevangeliou, Dimitra, Michalopoulos, Ioannis, Sideridou, Maria, Tsimaratou, Katerina, Christodoulou, Ioannis, Pyrillou, Katerina, Gorgoulis, Vassilis, Vlahopoulos, Spiros, Zoumpourlis, Vassilis
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3411716/ https://www.ncbi.nlm.nih.gov/pubmed/22870269 http://dx.doi.org/10.1371/journal.pone.0041957

Ejemplares similares

A Triphenylphosphonium-Functionalized Mitochondriotropic Nanocarrier for Efficient Co-Delivery of Doxorubicin and Chloroquine and Enhanced Antineoplastic Activity
por: Panagiotaki, Katerina N., et al.
Publicado: (2017)

Detection of Herplex Simplex Virus-1 and -2 in Cardiac Myxomas
por: Pateras, Ioannis S., et al.
Publicado: (2012)

ERα suppresses slug expression directly by transcriptional repression
por: Ye, Yin, et al.
Publicado: (2008)

Suitability of Human Mesenchymal Stem Cells Derived from Fetal Umbilical Cord (Wharton’s Jelly) as an Alternative In Vitro Model for Acute Drug Toxicity Screening
por: Christodoulou, Ioannis, et al.
Publicado: (2022)

YAP inhibits ERα and ER(+) breast cancer growth by disrupting a TEAD-ERα signaling axis
por: Li, Xu, et al.
Publicado: (2022)

Deciphering of a Putative GPER Recognition Domain in ERα and ERα36
por: Acramel, Alexandre, et al.
Publicado: (2022)

CDK11(p58) inhibits ERα-positive breast cancer invasion by targeting integrin β3 via the repression of ERα signaling
por: Chi, Yayun, et al.
Publicado: (2014)

Improved Budgeted Connected Domination and Budgeted Edge-Vertex Domination
por: Lamprou, Ioannis, et al.
Publicado: (2020)

Super-enhancer-controlled positive feedback loop BRD4/ERα–RET–ERα promotes ERα-positive breast cancer
por: Zheng, Zao-zao, et al.
Publicado: (2022)

miRNA-Guided Regulation of Mesenchymal Stem Cells Derived from the Umbilical Cord: Paving the Way for Stem-Cell Based Regeneration and Therapy
por: Thomaidou, Arsinoe C., et al.
Publicado: (2023)

Comparative Evaluation of Human Mesenchymal Stem Cells of Fetal (Wharton's Jelly) and Adult (Adipose Tissue) Origin during Prolonged In Vitro Expansion: Considerations for Cytotherapy
por: Christodoulou, I., et al.
Publicado: (2013)

Mesenchymal stem cells in preclinical cancer cytotherapy: a systematic review
por: Christodoulou, Ioannis, et al.
Publicado: (2018)

Prevention of Obesity and Insulin Resistance by Estrogens Requires ERα Activation Function-2 (ERαAF-2), Whereas ERαAF-1 Is Dispensable
por: Handgraaf, Sandra, et al.
Publicado: (2013)

Are common fragile sites merely structural domains or highly organized “functional” units susceptible to oncogenic stress?
por: Georgakilas, Alexandros G., et al.
Publicado: (2014)

Influence of Cellular ERα/ERβ Ratio on the ERα-Agonist Induced Proliferation of Human T47D Breast Cancer Cells
por: Covaleda, Ana M. Sotoca, et al.
Publicado: (2008)

ΔNp63α expression induces loss of cell adhesion in triple-negative breast cancer cells
por: Nekulova, Marta, et al.
Publicado: (2016)

Cdc6 expression represses E-cadherin transcription and activates adjacent replication origins
por: Sideridou, Maria, et al.
Publicado: (2011)

Tamoxifen may prevent both ER+ and ER- breast cancers and select for ER- carcinogenesis: an alternative hypothesis
por: Esserman, Laura J, et al.
Publicado: (2005)

Role of SUMOylation in differential ERα transcriptional repression by tamoxifen and fulvestrant in breast cancer cells
por: Traboulsi, Tatiana, et al.
Publicado: (2018)

Z-ligustilide restores tamoxifen sensitivity of ERα negative breast cancer cells by reversing MTA1/IFI16/HDACs complex mediated epigenetic repression of ERα
por: Ma, Hui, et al.
Publicado: (2017)

Expression of oestrogen receptors, ERα, ERβ, and ERβ variants, in endometrial cancers and evidence that prostaglandin F may play a role in regulating expression of ERα
por: Collins, Frances, et al.
Publicado: (2009)

Epigenetic reactivation of estrogen receptor-α (ERα) by genistein enhances hormonal therapy sensitivity in ERα-negative breast cancer
por: Li, Yuanyuan, et al.
Publicado: (2013)

Estrogen Signaling in ERα-Negative Breast Cancer: ERβ and GPER
por: Girgert, Rainer, et al.
Publicado: (2019)

Widespread PERK-dependent repression of ER targets in response to ER stress
por: Gonen, Nir, et al.
Publicado: (2019)

Proteasome inhibition represses ERα gene expression in ER+ cells- a new link between proteasome activity and estrogen signaling in breast cancer
por: Powers, Ginny L., et al.
Publicado: (2009)

Human estrogen receptor-α (ER-α) transactivation by selective estrogen receptor modulators (SERMs) on VIT regulatory region in ER-α-negative breast cancer cell line Evsa-T transiently transfected by ER-α
por: Nyamagana Butera, IP, et al.
Publicado: (2001)

Association of TRPS1 gene with different EMT markers in ERα-positive and ERα-negative breast cancer
por: Su, Peng, et al.
Publicado: (2014)

Respective role of membrane and nuclear estrogen receptor (ER) α in the mandible of growing mice: Implications for ERα modulation
por: Vinel, Alexia, et al.
Publicado: (2018)

MiR-signing gastrointestinal (con-)tract cancer
por: Gorgoulis, Vassilis G., et al.
Publicado: (2017)

ERβ1 Sensitizes and ERβ2 Desensitizes ERα-Positive Breast Cancer Cells to the Inhibitory Effects of Tamoxifen, Fulvestrant and Their Combination with All-Trans Retinoic Acid
por: Meligova, Aggeliki K., et al.
Publicado: (2023)

Cyclopia Extracts Act as ERα Antagonists and ERβ Agonists, In Vitro and In Vivo
por: Visser, Koch, et al.
Publicado: (2013)

ERα and ERβ co-expression: An indicator of aggressive tumors and hormonal sensitivity
por: Oueslati, Mohamed, et al.
Publicado: (2017)

The Co-Expression of Estrogen Receptors ERα, ERβ, and GPER in Endometrial Cancer
por: Hojnik, Marko, et al.
Publicado: (2023)

Characterizing the selectivity of ER α-glucosidase inhibitors
por: O’Keefe, Sarah, et al.
Publicado: (2019)

Genetically-modified stem cells in treatment of human diseases: Tissue kallikrein (KLK1)-based targeted therapy (Review)
por: Devetzi, Marina, et al.
Publicado: (2018)

TNFα Enhances Tamoxifen Sensitivity through Dissociation of ERα-p53-NCOR1 Complexes in ERα-Positive Breast Cancer
por: Kim, Hyunhee, et al.
Publicado: (2021)

The correlation between DNMT1 and ERα expression and the methylation status of ERα, and its clinical significance in breast cancer
por: ZHANG, WEIJIE, et al.
Publicado: (2016)

Correction: Cyclopia Extracts Act as ERα Antagonists and ERβ Agonists, In Vitro and In Vivo
por: Visser, Koch, et al.
Publicado: (2013)

Differential Roles of ERα and ERβ in Normal and Neoplastic Development in the Mouse Mammary Gland
por: Mehta, Rajendra G., et al.
Publicado: (2014)

Interaction of Coumarin Phytoestrogens with ER(α) and ER(β): A Molecular Dynamics Simulation Study
por: Wang, Ting, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_ure0albq450r01ov6k4m6n6gnn