High-Throughput Genotyping in Metastatic Esophageal Squamous Cell Carcinoma Identifies Phosphoinositide-3-Kinase and BRAF Mutations

BACKGROUND: Given the high incidence of metastatic esophageal squamous cell carcinoma, especially in Asia, we screened for the presence of somatic mutations using OncoMap platform with the aim of defining subsets of patients who may be potential candidate for targeted therapy. METHODS AND MATERIALS:...

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Detalles Bibliográficos
Autores principales: Maeng, Chi Hoon, Lee, Jeeyun, van Hummelen, Paul, Park, Se Hoon, Palescandolo, Emanuele, Jang, Jiryeon, Park, Ha Young, Kang, So Young, MacConaill, Laura, Kim, Kyoung-Mee, Shim, Young-Mog
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3411721/
https://www.ncbi.nlm.nih.gov/pubmed/22870241
http://dx.doi.org/10.1371/journal.pone.0041655

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