Protective Roles of DMP1 in High Phosphate Homeostasis

PURPOSE: Dmp1 (dentin matrix protein1) null mice (Dmp1(−/−)) display hypophosphatemic rickets with a sharp increase in fibroblast growth factor 23 (FGF23). Disruption of Klotho (the obligatory co-receptor of FGF23) results in hyperphosphatemia with ectopic calcifications formed in blood vessels and...

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Detalles Bibliográficos
Autores principales: Rangiani, Afsaneh, Cao, Zhengguo, Sun, Yao, Lu, Yongbo, Gao, Tian, Yuan, Baozhi, Rodgers, Anika, Qin, Chunlin, Kuro-o, Makoto, Feng, Jian Q.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3411740/
https://www.ncbi.nlm.nih.gov/pubmed/22879941
http://dx.doi.org/10.1371/journal.pone.0042329

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