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Computational Identification of Novel Amino-Acid Interactions in HIV Gag via Correlated Evolution

Pairs of amino acid positions that evolve in a correlated manner are proposed to play important roles in protein structure or function. Methods to detect them might fare better with families for which sequences of thousands of closely related homologs are available than families with only a few dist...

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Detalles Bibliográficos
Autores principales: Kalinina, Olga V., Oberwinkler, Heike, Glass, Bärbel, Kräusslich, Hans-Georg, Russell, Robert B., Briggs, John A. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3411748/
https://www.ncbi.nlm.nih.gov/pubmed/22879995
http://dx.doi.org/10.1371/journal.pone.0042468