Cargando…

SPARC Is a Key Regulator of Proliferation, Apoptosis and Invasion in Human Ovarian Cancer

BACKGROUND: Secreted protein acidic and rich in cysteine (SPARC), a calcium-binding matricellular glycoprotein, is implicated in the progression of many cancers. In this study, we investigated the expression and function of SPARC in ovarian cancer. METHODS: cDNA microarray analysis was performed to...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Jie, Wang, Mei, Xi, Bo, Xue, Jian, He, Dan, Zhang, Jie, Zhao, Yueran
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3411787/ https://www.ncbi.nlm.nih.gov/pubmed/22879971 http://dx.doi.org/10.1371/journal.pone.0042413

Ejemplares similares

Targeting SPARC by lentivirus-mediated RNA interference inhibits cervical cancer cell growth and metastasis
por: Chen, Jie, et al.
Publicado: (2012)

SPARC Inhibits Metabolic Plasticity in Ovarian Cancer
por: Naczki, Christine, et al.
Publicado: (2018)

Effect of metformin on the proliferation, apoptosis, invasion and autophagy of ovarian cancer cells
por: Zou, Ge, et al.
Publicado: (2019)

MiRNA-211 suppresses cell proliferation, migration and invasion by targeting SPARC in human hepatocellular carcinoma
por: Deng, Biao, et al.
Publicado: (2016)

SPARC Overexpression Promotes Liver Cancer Cell Proliferation and Tumor Growth
por: Gao, Zhao-wei, et al.
Publicado: (2021)

Downregulation of SPARC Expression Inhibits the Invasion of Human Trophoblast Cells In Vitro
por: Jiang, Yahong, et al.
Publicado: (2013)

Downregulation of SPARC expression decreases gastric cancer cellular invasion and survival
por: Yin, Jie, et al.
Publicado: (2010)

MicroRNA-211 suppresses prostate cancer proliferation by targeting SPARC
por: Hao, Peng, et al.
Publicado: (2018)

miR-211 inhibits proliferation, invasion and migration of cervical cancer via targeting SPARC
por: Qu, Xuqin, et al.
Publicado: (2018)

Retraction Note: MiRNA-211 suppresses cell proliferation, migration and invasion by targeting SPARC in human hepatocellular carcinoma
por: Deng, Biao, et al.
Publicado: (2023)

Regulation of the bi-directional cross-talk between ovarian cancer cells and adipocytes by SPARC
por: John, Bincy, et al.
Publicado: (2019)

SPARC: a matricellular regulator of tumorigenesis
por: Arnold, Shanna A., et al.
Publicado: (2009)

MicroRNA-592 promotes cell proliferation, migration and invasion in colorectal cancer by directly targeting SPARC
por: Pan, Zhenguo, et al.
Publicado: (2021)

SPARC's Initiative
por: Alison Buckholtz
Publicado: (2002)

Overexpression of SPARC correlates with poor prognosis in patients with cervical carcinoma and regulates cancer cell epithelial-mesenchymal transition
por: SHI, DEHUAN, et al.
Publicado: (2016)

Impact of Fibroblast-Derived SPARC on Invasiveness of Colorectal Cancer Cells
por: Drev, Daniel, et al.
Publicado: (2019)

Baicalin Regulates Proliferation, Apoptosis, Migration, and Invasion in Mesothelioma
por: Xu, Wen-Fei, et al.
Publicado: (2019)

Shikonin Inhibits Cholangiocarcinoma Cell Line QBC939 by Regulating Apoptosis, Proliferation, and Invasion
por: Liu, Chang, et al.
Publicado: (2021)

The circular RNA circSPARC enhances the migration and proliferation of colorectal cancer by regulating the JAK/STAT pathway
por: Wang, Jiaqi, et al.
Publicado: (2021)

Combination of Fenretinide and Selenite Inhibits Proliferation and Induces Apoptosis in Ovarian Cancer Cells
por: Liu, Jie, et al.
Publicado: (2013)

Pten regulates collagen fibrillogenesis by fibroblasts through SPARC
por: Jones, Caitlin E., et al.
Publicado: (2021)

SPARC expression in CML is associated to imatinib treatment and to inhibition of leukemia cell proliferation
por: Giallongo, Cesarina, et al.
Publicado: (2013)

Evolution of dental tissue mineralization: an analysis of the jawed vertebrate SPARC and SPARC-L families
por: Enault, Sébastien, et al.
Publicado: (2018)

Exosomal microRNA-205 is involved in proliferation, migration, invasion, and apoptosis of ovarian cancer cells via regulating VEGFA
por: Wang, Lijun, et al.
Publicado: (2019)

Overexpression of EFEMP1 Correlates with Tumor Progression and Poor Prognosis in Human Ovarian Carcinoma
por: Chen, Jie, et al.
Publicado: (2013)

SPARC functions as an inhibitor of adipogenesis
por: Nie, Jing, et al.
Publicado: (2009)

SPARC–Dependent Cardiomyopathy in Drosophila
por: Hartley, Paul S., et al.
Publicado: (2016)

Circular_0086414 induces SPARC like 1 (SPARCL1) production to inhibit esophageal cancer cell proliferation, invasion and glycolysis and induce cell apoptosis by sponging miR-1290
por: Jiang, Qingfeng, et al.
Publicado: (2022)

Dihydroartemisinin induces apoptosis and inhibits proliferation, migration, and invasion in epithelial ovarian cancer via inhibition of the hedgehog signaling pathway
por: Liu, Yanmei, et al.
Publicado: (2018)

Divergent Expression of SPARC, SPARC-L, and SCPP Genes During Jawed Vertebrate Cartilage Mineralization
por: Romero, Adrian, et al.
Publicado: (2021)

SPARC Negatively Correlates With Prognosis After Transarterial Chemoembolization and Facilitates Proliferation and Metastasis of Hepatocellular Carcinoma via ERK/MMP Signaling Pathways
por: Liu, Yao, et al.
Publicado: (2020)

Secreted Protein Acidic and Rich in Cysteine (SPARC) Enhances Cell Proliferation, Migration, and Epithelial Mesenchymal Transition, and SPARC Expression is Associated with Tumor Grade in Head and Neck Cancer
por: Chang, Chih-Hau, et al.
Publicado: (2017)

Fibulin-4 is associated with tumor progression and a poor prognosis in ovarian carcinomas
por: Chen, Jie, et al.
Publicado: (2015)

Relationship and prognostic significance of SPARC and VEGF protein expression in colon cancer
por: Liang, Jian-fang, et al.
Publicado: (2010)

Thrombospondin-2 and SPARC/osteonectin are critical regulators of bone remodeling
por: Delany, Anne M., et al.
Publicado: (2009)

SPARC Levels Modulate the Capacity of Mitomycin to Inhibit the Proliferation of Human Tenon's Capsule Fibroblasts
por: Guo, Yuanyuan, et al.
Publicado: (2020)

CASC11 Overexpression Predicts Poor Prognosis and Regulates Cell Proliferation and Apoptosis in Ovarian Carcinoma
por: Cui, Ying, et al.
Publicado: (2020)

Dexmedetomidine Regulates Proliferation, Apoptosis, Migration, and Invasion in Ovarian Cancer Cells via MiR-155-HIF-1α Axis
por: Zheng, Lihong, et al.
Publicado: (2019)

SPARC Regulates Transforming Growth Factor Beta Induced (TGFBI) Extracellular Matrix Deposition and Paclitaxel Response in Ovarian Cancer Cells
por: Tumbarello, David A., et al.
Publicado: (2016)

The Function of SPARC as a Mediator of Fibrosis
por: Trombetta-eSilva, Jessica, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_rvg55d5e5v8sg95g72vmh8uov3