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The Colitis-Associated Transcriptional Profile of Commensal Bacteroides thetaiotaomicron Enhances Adaptive Immune Responses to a Bacterial Antigen

BACKGROUND: Inflammatory bowel diseases (IBD) may be caused in part by aberrant immune responses to commensal intestinal microbes including the well-characterized anaerobic gut commensal Bacteroides thetaiotaomicron (B. theta). Healthy, germ-free HLA-B27 transgenic (Tg) rats develop chronic colitis...

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Detalles Bibliográficos
Autores principales: Hansen, Jonathan J., Huang, Yong, Peterson, Daniel A., Goeser, Laura, Fan, Ting-Jia, Chang, Eugene B., Sartor, R. Balfour
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3411805/
https://www.ncbi.nlm.nih.gov/pubmed/22880065
http://dx.doi.org/10.1371/journal.pone.0042645